1305 O’Brien

Menlo Park, CA

Bringing new life to a nondescript warehouse, Tarlton Properties’ adaptively repurposed 1305 O’Brien to become a state-of-the art R&D and manufacturing headquarters for Pacific Biosciences. With its deep canopy, clear glazing and steel supports, the new entrance welcomes employees to the modernized workplace. The entry opens to a two-story lobby space that furthers Pacific Biosciences goal of facilitating interaction and collaboration across disciplines. Taking advantage of the existing high-bay warehouse, a two-story, tiered meeting space was added to the center of the building to create an all-hands gathering space. The new building—evocative of the industrial character of the surrounding neighborhood—is now an inspiring component for the ongoing modernization of the sixteen-building Menlo Business Park.

project highlights

  • 220,500-sf renovation
  • new entry and facade upgrades
  • new landscaping and site work
  • centralized social spaces
  • manufacturing spaces
  • electronics labs
  • chemistry and biology labs


  • Gold Nugget, Merit Award for Best Rehabilitation Project